Critic Consensus: It doesn't take its terrific premise quite as far as it should, but Splice is a smart, well-acted treat for horror fans.
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Critic Reviews for Splice
This Cronenbergian exploration of the perils of inter-species gene-splicing wrestles with some topical and disturbing ideas, but never quite pins them down.
[It's] witty, aware of its own craziness, and disarmingly insightful about the psychology of its characters.
A good horror flick always does metaphoric battle with our interior demons, and Splice summons them in impressive numbers.
What makes Splice morally compelling isn't the bioethics quandaries it raises so much as the way it delves into parenthood.
Audience Reviews for Splice
It is frustrating to see such a fantastic idea and amazing development lead to a disappointing ending. The whole film builds as an intelligent and compelling sci-fi drama until Vincenzo Natali finally decides in the last fifteen minutes that it should be in fact a stupid horror story.
Entertaining albeit stupid genetic experiment thriller that can't decide how it wants to make the audience feel about its creature. The somewhat lousy special effects do not exactly help creating a connection to the "monster". Another problem are the characters that range from idiotic, flat to downright unlikable. So overall everything that happens makes you feel entirely indifferent.
A pair of genetic biologists succeed in splicing the DNA of various creatures with that of a human being and the resulting life form begins to take over their lives as they try to hide their secret experiment. Splice is very much in the old "mad scientists play God and reap the consequences" school of horror stories, giving the Frankenstein formula a modern sci-fi spin. In fact the story interestingly stays away from the man makes monster idea for the early stages, preferring David Cronenberg style psychological horror, particularly during the rather disturbing Mommie Dearest sequence and when the bizarre sexual ambiguity of their creation becomes apparent. Disappointingly it soon settles back into the usual creature feature for an overly predictable finale which is a shame because it was actually starting to explore some interesting ideas. The production design is a little suspect (baby Dren looks suspiciously like an oven ready chicken with a rabbit's head) but Brody and Polley are as watchable as always and it's weird enough to maintain the attention for the duration, but it's nowhere near as inventive as Prometheus which covered a lot of the same ground.
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